PEOPLE

I recently completed my Ph.D. in Medicinal Chemistry at the University of Rhode Island, where I focused on oligonucleotide synthesis, DNA-protein crosslink repair, and mass spectrometry-based bioanalysis. My research combined chemical biology and analytical chemistry to study AlkB-family enzymes and nucleic acid damage.

1. Peng, Z.; Ye, Y.-S.; Wu, Q.* Structural diversity and biological activities of secondary metabolites from the marine soft coral Clavularia. MarineMedicine 2025, accepted.

Yansong received his Ph.D. from the Kunming Institute of Botany, Chinese Academy of Sciences, where he focused on the structure and bioactivity of natural Polycyclic Polyprenylated Acylphloroglucinol (PPAP) from Hypericum genus. He subsequently carried out postdoctoral research at the Kunming Institute of Botany, University of South Carolina, and University of Texas at Austin.

Yansong’s research lies at the interface of chemistry, metabolomics, and microbiology. He is particularly interested in exploring how gut microbes produce small-molecule natural products and how these metabolites mediate host–microbe ecological interactions. His work aims to uncover novel bioactive molecules and provide new insights into the chemical basis of host–microbiome communication.

3. Gbadebo, O. S.; Masibag, A. G.; Rosario, M. E.; He, R.; Ye, Y.-S.; Gomez-Chiarri, M.; Wu, Q.*; Rowley, D. C.* Submitted.

2. Peng, Z.; Ye, Y.-S.; Wu, Q.* Structural diversity and biological activities of secondary metabolites from the marine soft coral Clavularia. MarineMedicine 2025, accepted.

1. Ranson, H. J.; Ye, Y.-S.; Petukhova, V. Z.; Green-Saxena, A.; He, R.; Sun, J.; Godugu, B.; Sanchez, L. M.; Wu, Q.*; Rowley, D. C.* Lipopeptides and antibiotics from a marine Bacillus pumilus mediate a potential ‘catch and kill’ effect on pathogenetic Vibrio parahaemolyticus. mSystems 2025, accepted.